Fragile Sites,Chromosome
《英文msh詞典》Fragile Sites,Chromosome
[同義詞] Fragile Sites,Chromosome
[主題詞] Chromosome Fragile Sites
[中文釋義] 脆性位點,染色體
[英文釋義] Specific loci that show up during KARYOTYPING as a gap (an uncondensed stretch in closer views) on a CHROMATID arm after culturing cells under specific conditions. These sites are associated with an increase in CHROMOSOME FRAGILITY. They are classified as common or rare,and by the specific culture conditions under which they develop. Fragile site loci are named by the letters FRA followed by a designation for the specific chromosome,and a letter which refers to which fragile site of that chromosome (e.g. FRAXA refers to fragile site A on the X chromosome. It is a rare,folic acid-sensitive fragile site associated with FRAGILE X SYNDROME.)